ESRESR stands for erythrocyte sedimentation
rate. It is a test that indirectly measures how much inflammation is in
the body. However, it rarely leads directly to a specific diagnosis.
How the Test is PerformedBlood is drawn from a vein, usually from the inside of the elbow or
the back of the hand. The site is cleaned with germ-killing medicine
(antiseptic). The health care provider wraps an elastic band around the
upper arm to apply pressure to the area and make the vein swell with
blood.
Next, the health care provider gently inserts a needle into
the vein. The blood collects into an airtight vial or tube attached to
the needle. The elastic band is removed from your arm.
Once the
blood has been collected, the needle is removed, and the puncture site
is covered to stop any bleeding.
In infants or young children, a
sharp tool called a lancet may be used to puncture the skin and make it
bleed. The blood collects into a small glass tube called a pipette, or
onto a slide or test strip. A bandage may be placed over the area if
there is any bleeding.
The blood sample is sent to a lab. The test
measures how fast red blood cells called erythrocytes fall to the
bottom of a tall, thin tube.
How to Prepare for the TestThere are no special preparations needed.
How the Test Will FeelWhen the needle is inserted to draw blood, some people feel moderate
pain, while others feel only a prick or stinging sensation. Afterward,
there may be some throbbing.
Why the Test is PerformedThis test can be used to monitor inflammatory or cancerous diseases.
It is a screening test, which means it cannot be used to diagnose a
specific disorder.
However, it is useful in detecting and
monitoring tuberculosis,
tissue death, certain forms of arthritis, autoimmune disorders, and
inflammatory diseases that cause vague symptoms.
Normal ResultsAdults (Westergren method):
- Men under 50 years old: less
than 15 mm/hr
- Men over 50 years old: less than 20 mm/hr
- Women
under 50 years old: less than 20 mm/hr
- Women over 50 years old:
less than 30 mm/hr
Children (Westergren method):
- Newborn:
0 to 2 mm/hr
- Neonatal to puberty: 3 to 13 mm/hr
Note:
mm/hr. = millimeters per hour
What Abnormal Results MeanAn increased ESR rate may be due to:
- Anemia
- Endocarditis
- Kidney
disease
- Osteomyelitis
- Pregnancy
- Rheumatic
fever
- Rheumatoid
arthritis
- Syphilis
- Systemic
lupus erythematosus
- Thyroid
disease
- Tuberculosis
- Other inflammatory conditions
Very
high ESR levels occur with:
- Body-wide (systemic) infection
- Giant
cell arteritis
- Hyperfibrinogenemia (increased fibrinogen
levels in the blood)
- Multiple
myeloma
- Macroglobulinemia
- primary
- Necrotizing
vasculitis
- Polymyalgia
rheumatica
Lower-than-normal levels occur with:
- Congestive
heart failure
- Hyperviscosity
- Hypofibrinogenemia
(decreased fibrinogen levels)
- Low plasma protein (due to liver
or kidney disease)
- Polycythemia
- Sickle
cell anemia
Additional conditions that may affect test
results:
- Allergic
vasculitis
- Atrial
myxoma
- Autoimmune
hepatitis
- Endometritis
- Eosinophilic
fasciitis
- Erysipelas
- Juvenile rheumatoid arthritis
- Legionnaire's
disease
- Osteomyelitis
- Pelvic inflammatory disease
- Pericarditis
after a heart attack
- Retroperitoneal fibrosis
- Skin
lesion of blastomycosis
- Subacute thyroiditis
- Scleroderma
RisksVeins and arteries vary in size from one patient to another and from
one side of the body to the other. Obtaining a blood sample from some
people may be more difficult than from others.
Other risks
associated with having blood drawn are slight but may include:
- Excessive
bleeding
- Fainting or feeling light-headed
- Hematoma
(blood accumulating under the skin)
- Infection (a slight risk any
time the skin is broken)